[tpcloud]

2024

Ortigoza-Escobar JD Kaiyrzhanov R, Stringer BW

Clinical and Molecular Spectrum of Autosomal Recessive CA8-Related Cerebellar Ataxia Journal Article

In: Movement Disorder, 2024.

Links | BibTeX | Tags:

Tromp A. Guo F., Wang H.

Cre-Lox miRNA-delivery technology optimized for inducible microRNA and gene-silencing studies in zebrafish Journal Article

In: BioRxiv, 2024.

Links | BibTeX | Tags:

2023

Ariotti N Hall TE, Lo HP

Flexing fish: cell surface plasticity in response to shape change in the whole organism. Journal Article

In: Current Biology, 2023.

Links | BibTeX | Tags:

Wang H. Tromp A., Hall TE

Optimising the zebrafish Cre/Lox toolbox. Codon improved iCre, new gateway tools, Cre protein and guidelines. Journal Article

In: Frontiers in Physiology, 2023.

Links | BibTeX | Tags:

2022

Marquez-Legorreta, Emmanuel; Constantin, Lena; Piber, Marielle; Favre-Bulle, Itia A; Taylor, Michael A; Blevins, Ann S; Giacomotto, Jean; Bassett, Dani S; Vanwalleghem, Gilles C; Scott, Ethan K

Brain-wide visual habituation networks in wild type and fmr1 zebrafish Journal Article

In: Nat Commun, vol. 13, no. 1, pp. 895, 2022, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags:

Restuadi, Restuadi; Steyn, Frederik J; Kabashi, Edor; Ngo, Shyuan T; Cheng, Fei-Fei; Nabais, Marta F; Thompson, Mike J; Qi, Ting; Wu, Yang; Henders, Anjali K; Wallace, Leanne; Bye, Chris R; Turner, Bradley J; Ziser, Laura; Mathers, Susan; McCombe, Pamela A; Needham, Merrilee; Schultz, David; Kiernan, Matthew C; van Rheenen, Wouter; van den Berg, Leonard H; Veldink, Jan H; Ophoff, Roel; Gusev, Alexander; Zaitlen, Noah; McRae, Allan F; Henderson, Robert D; Wray, Naomi R; Giacomotto, Jean; Garton, Fleur C

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1 Journal Article

In: Genome Med, vol. 14, no. 1, pp. 7, 2022, ISSN: 1756-994X.

Abstract | Links | BibTeX | Tags:

2021

Tromp, Alisha; Robinson, Kate; Hall, Thomas E; Mowry, Bryan; Giacomotto, Jean

Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions Journal Article

In: G3 (Bethesda), vol. 11, no. 12, 2021, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags:

Lo, Harriet P; Lim, Ye-Wheen; Xiong, Zherui; Martel, Nick; Ferguson, Charles; Ariotti, Nicholas; Giacomotto, Jean; Rae, James; Floetenmeyer, Matthias; Moradi, Shayli Varasteh; Gao, Ya; Tillu, Vikas A; Xia, Di; Wang, Huang; Rahnama, Samira; Nixon, Susan J; Bastiani, Michele; Day, Ryan D; Smith, Kelly A; Palpant, Nathan J; Johnston, Wayne A; Alexandrov, Kirill; Collins, Brett M; Hall, Thomas E; Parton, Robert G

Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle Journal Article

In: J Cell Biol, vol. 220, no. 12, 2021, ISSN: 1540-8140.

Abstract | Links | BibTeX | Tags:

Butti, Zoé; Pan, Yingzhou Edward; Giacomotto, Jean; Patten, Shunmoogum A

Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish Journal Article

In: Commun Biol, vol. 4, no. 1, pp. 792, 2021, ISSN: 2399-3642.

Abstract | Links | BibTeX | Tags:

Tromp, Alisha; Mowry, Bryan; Giacomotto, Jean

Neurexins in autism and schizophrenia-a review of patient mutations, mouse models and potential future directions Journal Article

In: Mol Psychiatry, vol. 26, no. 3, pp. 747–760, 2021, ISSN: 1476-5578.

Abstract | Links | BibTeX | Tags:

2020

Wang, Dan; Himaya, S W A; Giacomotto, Jean; Hasan, Md Mahadhi; Cardoso, Fernanda C; Ragnarsson, Lotten; Lewis, Richard J

Characterisation of d-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator Journal Article

In: Mar Drugs, vol. 18, no. 7, 2020, ISSN: 1660-3397.

Abstract | Links | BibTeX | Tags:

Gormal, Rachel S; Padmanabhan, Pranesh; Kasula, Ravikiran; Bademosi, Adekunle T; Coakley, Sean; Giacomotto, Jean; Blum, Ailisa; Joensuu, Merja; Wallis, Tristan P; Lo, Harriet P; Budnar, Srikanth; Rae, James; Ferguson, Charles; Bastiani, Michele; Thomas, Walter G; Pardon, Els; Steyaert, Jan; Yap, Alpha S; Goodhill, Geoffrey J; Hilliard, Massimo A; Parton, Robert G; Meunier, Frédéric A

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies Journal Article

In: Proc Natl Acad Sci U S A, vol. 117, no. 48, pp. 30476–30487, 2020, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags:

2019

Dutt, Mriga; Giacomotto, Jean; Ragnarsson, Lotten; Andersson, Åsa; Brust, Andreas; Dekan, Zoltan; Alewood, Paul F; Lewis, Richard J

The α-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa Journal Article

In: Sci Rep, vol. 9, no. 1, pp. 17841, 2019, ISSN: 2045-2322.

Abstract | Links | BibTeX | Tags:

Periyasamy, Sathish; John, Sujit; Padmavati, Raman; Rajendren, Preeti; Thirunavukkarasu, Priyadarshini; Gratten, Jacob; Vinkhuyzen, Anna; McRae, Allan; Holliday, Elizabeth G; Nyholt, Dale R; Nancarrow, Derek; Bakshi, Andrew; Hemani, Gibran; Nertney, Deborah; Smith, Heather; Filippich, Cheryl; Patel, Kalpana; Fowdar, Javed; McLean, Duncan; Tirupati, Srinivasan; Nagasundaram, Arunkumar; Gundugurti, Prasad Rao; Selvaraj, Krishnamurthy; Jegadeesan, Jayaprakash; Jorde, Lynn B; Wray, Naomi R; Brown, Matthew A; Suetani, Rachel; Giacomotto, Jean; Thara, Rangaswamy; Mowry, Bryan J

Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study Journal Article

In: JAMA Psychiatry, vol. 76, no. 10, pp. 1026–1034, 2019, ISSN: 2168-6238.

Abstract | Links | BibTeX | Tags:

2017

Lim, Ye-Wheen; Lo, Harriet P; Ferguson, Charles; Martel, Nick; Giacomotto, Jean; Gomez, Guillermo A; Yap, Alpha S; Hall, Thomas E; Parton, Robert G

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development Journal Article

In: Curr Biol, vol. 27, no. 13, pp. 1968–1981.e7, 2017, ISSN: 1879-0445.

Abstract | Links | BibTeX | Tags:

2016

Svahn, Adam J; Giacomotto, Jean; Graeber, Manuel B; Rinkwitz, Silke; Becker, Thomas S

miR-124 Contributes to the functional maturity of microglia Journal Article

In: Dev Neurobiol, vol. 76, no. 5, pp. 507–518, 2016, ISSN: 1932-846X.

Abstract | Links | BibTeX | Tags:

Giacomotto, J; Carroll, A P; Rinkwitz, S; Mowry, B; Cairns, M J; Becker, T S

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish Journal Article

In: Transl Psychiatry, vol. 6, pp. e818, 2016, ISSN: 2158-3188.

Abstract | Links | BibTeX | Tags:

Laird, Angela S; Mackovski, Nikolce; Rinkwitz, Silke; Becker, Thomas S; Giacomotto, Jean

Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages Journal Article

In: Hum Mol Genet, vol. 25, no. 9, pp. 1728–1738, 2016, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags:

2015

Ishibashi, Minaka; Manning, Elizabeth; Shoubridge, Cheryl; Krecsmarik, Monika; Hawkins, Thomas A; Giacomotto, Jean; Zhao, Ting; Mueller, Thomas; Bader, Patricia I; Cheung, Sau W; Stankiewicz, Pawel; Bain, Nicole L; Hackett, Anna; Reddy, Chilamakuri C S; Mechaly, Alejandro S; Peers, Bernard; Wilson, Stephen W; Lenhard, Boris; Bally-Cuif, Laure; Gecz, Jozef; Becker, Thomas S; Rinkwitz, Silke

Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene Journal Article

In: Hum Genet, vol. 134, no. 11-12, pp. 1163–1182, 2015, ISSN: 1432-1203.

Abstract | Links | BibTeX | Tags:

Himaya, S W A; Jin, Ai-Hua; Dutertre, Sébastien; Giacomotto, Jean; Mohialdeen, Hoshyar; Vetter, Irina; Alewood, Paul F; Lewis, Richard J

Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus Journal Article

In: J Proteome Res, vol. 14, no. 10, pp. 4372–4381, 2015, ISSN: 1535-3907.

Abstract | Links | BibTeX | Tags:

Giacomotto, Jean; Rinkwitz, Silke; Becker, Thomas S

Effective heritable gene knockdown in zebrafish using synthetic microRNAs Journal Article

In: Nat Commun, vol. 6, pp. 7378, 2015, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags:

Punnamoottil, Beena; Rinkwitz, Silke; Giacomotto, Jean; Svahn, Adam J; Becker, Thomas S

Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes Journal Article

In: Genesis, vol. 53, no. 5, pp. 321–328, 2015, ISSN: 1526-968X.

Abstract | Links | BibTeX | Tags:

2013

Giacomotto, Jean; Brouilly, Nicolas; Walter, Ludivine; Mariol, Marie-Christine; Berger, Joachim; Ségalat, Laurent; Becker, Thomas S; Currie, Peter D; Gieseler, Kathrin

Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy Journal Article

In: Hum Mol Genet, vol. 22, no. 22, pp. 4562–4578, 2013, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags:

2012

Djiotsa, Joachim; Verbruggen, Vincianne; Giacomotto, Jean; Ishibashi, Minaka; Manning, Elisabeth; Rinkwitz, Silke; Manfroid, Isabelle; Voz, Marianne L; Peers, Bernard

Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression Journal Article

In: BMC Dev Biol, vol. 12, pp. 37, 2012, ISSN: 1471-213X.

Abstract | Links | BibTeX | Tags:

Giacomotto, Jean; Ségalat, Laurent; Carre-Pierrat, Maïté; Gieseler, Kathrin

Caenorhabditis elegans as a chemical screening tool for the study o f neuromuscular disorders. Manual and semi-automated methods Journal Article

In: Methods, vol. 56, no. 1, pp. 103–113, 2012, ISSN: 1095-9130.

Abstract | Links | BibTeX | Tags:

2010

Giacomotto, Jean; Ségalat, Laurent

High-throughput screening and small animal models, where are we? Journal Article

In: Br J Pharmacol, vol. 160, no. 2, pp. 204–216, 2010, ISSN: 1476-5381.

Abstract | Links | BibTeX | Tags:

2009

Giacomotto, Jean; Pertl, Cordula; Borrel, Caroline; Walter, Maggie C; Bulst, Stefanie; Johnsen, Bob; Baillie, David L; Lochmüller, Hanns; Thirion, Christian; Ségalat, Laurent

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy Journal Article

In: Hum Mol Genet, vol. 18, no. 21, pp. 4089–4101, 2009, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags:

Blaise, Benjamin J; Giacomotto, Jean; Triba, Mohamed N; Toulhoat, Pierre; Piotto, Martial; Emsley, Lyndon; Ségalat, Laurent; Dumas, Marc-Emmanuel; Elena, Bénédicte

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance Journal Article

In: J Proteome Res, vol. 8, no. 5, pp. 2542–2550, 2009, ISSN: 1535-3893.

Abstract | Links | BibTeX | Tags:

2007

Blaise, Benjamin J; Giacomotto, Jean; Elena, Bénédicte; Dumas, Marc-Emmanuel; Toulhoat, Pierre; Ségalat, Laurent; Emsley, Lyndon

Metabotyping of Caenorhabditis elegans reveals latent phenotypes Journal Article

In: Proc Natl Acad Sci U S A, vol. 104, no. 50, pp. 19808–19812, 2007, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags:

2006

Carre-Pierrat, Maité; Mariol, Marie-Christine; Chambonnier, Lucie; Laugraud, Aurélie; Heskia, Fabienne; Giacomotto, Jean; Ségalat, Laurent

Blocking of striated muscle degeneration by serotonin in C. elegans Journal Article

In: J Muscle Res Cell Motil, vol. 27, no. 3-4, pp. 253–258, 2006, ISSN: 0142-4319.

Abstract | Links | BibTeX | Tags:

2024

Ortigoza-Escobar JD Kaiyrzhanov R, Stringer BW

Clinical and Molecular Spectrum of Autosomal Recessive CA8-Related Cerebellar Ataxia Journal Article

In: Movement Disorder, 2024.

Links | BibTeX | Tags:

Tromp A. Guo F., Wang H.

Cre-Lox miRNA-delivery technology optimized for inducible microRNA and gene-silencing studies in zebrafish Journal Article

In: BioRxiv, 2024.

Links | BibTeX | Tags:

2023

Ariotti N Hall TE, Lo HP

Flexing fish: cell surface plasticity in response to shape change in the whole organism. Journal Article

In: Current Biology, 2023.

Links | BibTeX | Tags:

Wang H. Tromp A., Hall TE

Optimising the zebrafish Cre/Lox toolbox. Codon improved iCre, new gateway tools, Cre protein and guidelines. Journal Article

In: Frontiers in Physiology, 2023.

Links | BibTeX | Tags:

2022

Marquez-Legorreta, Emmanuel; Constantin, Lena; Piber, Marielle; Favre-Bulle, Itia A; Taylor, Michael A; Blevins, Ann S; Giacomotto, Jean; Bassett, Dani S; Vanwalleghem, Gilles C; Scott, Ethan K

Brain-wide visual habituation networks in wild type and fmr1 zebrafish Journal Article

In: Nat Commun, vol. 13, no. 1, pp. 895, 2022, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags:

Restuadi, Restuadi; Steyn, Frederik J; Kabashi, Edor; Ngo, Shyuan T; Cheng, Fei-Fei; Nabais, Marta F; Thompson, Mike J; Qi, Ting; Wu, Yang; Henders, Anjali K; Wallace, Leanne; Bye, Chris R; Turner, Bradley J; Ziser, Laura; Mathers, Susan; McCombe, Pamela A; Needham, Merrilee; Schultz, David; Kiernan, Matthew C; van Rheenen, Wouter; van den Berg, Leonard H; Veldink, Jan H; Ophoff, Roel; Gusev, Alexander; Zaitlen, Noah; McRae, Allan F; Henderson, Robert D; Wray, Naomi R; Giacomotto, Jean; Garton, Fleur C

Functional characterisation of the amyotrophic lateral sclerosis risk locus GPX3/TNIP1 Journal Article

In: Genome Med, vol. 14, no. 1, pp. 7, 2022, ISSN: 1756-994X.

Abstract | Links | BibTeX | Tags:

2021

Tromp, Alisha; Robinson, Kate; Hall, Thomas E; Mowry, Bryan; Giacomotto, Jean

Pipeline for generating stable large genomic deletions in zebrafish, from small domains to whole gene excisions Journal Article

In: G3 (Bethesda), vol. 11, no. 12, 2021, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags:

Lo, Harriet P; Lim, Ye-Wheen; Xiong, Zherui; Martel, Nick; Ferguson, Charles; Ariotti, Nicholas; Giacomotto, Jean; Rae, James; Floetenmeyer, Matthias; Moradi, Shayli Varasteh; Gao, Ya; Tillu, Vikas A; Xia, Di; Wang, Huang; Rahnama, Samira; Nixon, Susan J; Bastiani, Michele; Day, Ryan D; Smith, Kelly A; Palpant, Nathan J; Johnston, Wayne A; Alexandrov, Kirill; Collins, Brett M; Hall, Thomas E; Parton, Robert G

Cavin4 interacts with Bin1 to promote T-tubule formation and stability in developing skeletal muscle Journal Article

In: J Cell Biol, vol. 220, no. 12, 2021, ISSN: 1540-8140.

Abstract | Links | BibTeX | Tags:

Butti, Zoé; Pan, Yingzhou Edward; Giacomotto, Jean; Patten, Shunmoogum A

Reduced C9orf72 function leads to defective synaptic vesicle release and neuromuscular dysfunction in zebrafish Journal Article

In: Commun Biol, vol. 4, no. 1, pp. 792, 2021, ISSN: 2399-3642.

Abstract | Links | BibTeX | Tags:

Tromp, Alisha; Mowry, Bryan; Giacomotto, Jean

Neurexins in autism and schizophrenia-a review of patient mutations, mouse models and potential future directions Journal Article

In: Mol Psychiatry, vol. 26, no. 3, pp. 747–760, 2021, ISSN: 1476-5578.

Abstract | Links | BibTeX | Tags:

2020

Wang, Dan; Himaya, S W A; Giacomotto, Jean; Hasan, Md Mahadhi; Cardoso, Fernanda C; Ragnarsson, Lotten; Lewis, Richard J

Characterisation of d-Conotoxin TxVIA as a Mammalian T-Type Calcium Channel Modulator Journal Article

In: Mar Drugs, vol. 18, no. 7, 2020, ISSN: 1660-3397.

Abstract | Links | BibTeX | Tags:

Gormal, Rachel S; Padmanabhan, Pranesh; Kasula, Ravikiran; Bademosi, Adekunle T; Coakley, Sean; Giacomotto, Jean; Blum, Ailisa; Joensuu, Merja; Wallis, Tristan P; Lo, Harriet P; Budnar, Srikanth; Rae, James; Ferguson, Charles; Bastiani, Michele; Thomas, Walter G; Pardon, Els; Steyaert, Jan; Yap, Alpha S; Goodhill, Geoffrey J; Hilliard, Massimo A; Parton, Robert G; Meunier, Frédéric A

Modular transient nanoclustering of activated β2-adrenergic receptors revealed by single-molecule tracking of conformation-specific nanobodies Journal Article

In: Proc Natl Acad Sci U S A, vol. 117, no. 48, pp. 30476–30487, 2020, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags:

2019

Dutt, Mriga; Giacomotto, Jean; Ragnarsson, Lotten; Andersson, Åsa; Brust, Andreas; Dekan, Zoltan; Alewood, Paul F; Lewis, Richard J

The α-adrenoceptor inhibitor ρ-TIA facilitates net hunting in piscivorous Conus tulipa Journal Article

In: Sci Rep, vol. 9, no. 1, pp. 17841, 2019, ISSN: 2045-2322.

Abstract | Links | BibTeX | Tags:

Periyasamy, Sathish; John, Sujit; Padmavati, Raman; Rajendren, Preeti; Thirunavukkarasu, Priyadarshini; Gratten, Jacob; Vinkhuyzen, Anna; McRae, Allan; Holliday, Elizabeth G; Nyholt, Dale R; Nancarrow, Derek; Bakshi, Andrew; Hemani, Gibran; Nertney, Deborah; Smith, Heather; Filippich, Cheryl; Patel, Kalpana; Fowdar, Javed; McLean, Duncan; Tirupati, Srinivasan; Nagasundaram, Arunkumar; Gundugurti, Prasad Rao; Selvaraj, Krishnamurthy; Jegadeesan, Jayaprakash; Jorde, Lynn B; Wray, Naomi R; Brown, Matthew A; Suetani, Rachel; Giacomotto, Jean; Thara, Rangaswamy; Mowry, Bryan J

Association of Schizophrenia Risk With Disordered Niacin Metabolism in an Indian Genome-wide Association Study Journal Article

In: JAMA Psychiatry, vol. 76, no. 10, pp. 1026–1034, 2019, ISSN: 2168-6238.

Abstract | Links | BibTeX | Tags:

2017

Lim, Ye-Wheen; Lo, Harriet P; Ferguson, Charles; Martel, Nick; Giacomotto, Jean; Gomez, Guillermo A; Yap, Alpha S; Hall, Thomas E; Parton, Robert G

Caveolae Protect Notochord Cells against Catastrophic Mechanical Failure during Development Journal Article

In: Curr Biol, vol. 27, no. 13, pp. 1968–1981.e7, 2017, ISSN: 1879-0445.

Abstract | Links | BibTeX | Tags:

2016

Svahn, Adam J; Giacomotto, Jean; Graeber, Manuel B; Rinkwitz, Silke; Becker, Thomas S

miR-124 Contributes to the functional maturity of microglia Journal Article

In: Dev Neurobiol, vol. 76, no. 5, pp. 507–518, 2016, ISSN: 1932-846X.

Abstract | Links | BibTeX | Tags:

Giacomotto, J; Carroll, A P; Rinkwitz, S; Mowry, B; Cairns, M J; Becker, T S

Developmental suppression of schizophrenia-associated miR-137 alters sensorimotor function in zebrafish Journal Article

In: Transl Psychiatry, vol. 6, pp. e818, 2016, ISSN: 2158-3188.

Abstract | Links | BibTeX | Tags:

Laird, Angela S; Mackovski, Nikolce; Rinkwitz, Silke; Becker, Thomas S; Giacomotto, Jean

Tissue-specific models of spinal muscular atrophy confirm a critical role of SMN in motor neurons from embryonic to adult stages Journal Article

In: Hum Mol Genet, vol. 25, no. 9, pp. 1728–1738, 2016, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags:

2015

Ishibashi, Minaka; Manning, Elizabeth; Shoubridge, Cheryl; Krecsmarik, Monika; Hawkins, Thomas A; Giacomotto, Jean; Zhao, Ting; Mueller, Thomas; Bader, Patricia I; Cheung, Sau W; Stankiewicz, Pawel; Bain, Nicole L; Hackett, Anna; Reddy, Chilamakuri C S; Mechaly, Alejandro S; Peers, Bernard; Wilson, Stephen W; Lenhard, Boris; Bally-Cuif, Laure; Gecz, Jozef; Becker, Thomas S; Rinkwitz, Silke

Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene Journal Article

In: Hum Genet, vol. 134, no. 11-12, pp. 1163–1182, 2015, ISSN: 1432-1203.

Abstract | Links | BibTeX | Tags:

Himaya, S W A; Jin, Ai-Hua; Dutertre, Sébastien; Giacomotto, Jean; Mohialdeen, Hoshyar; Vetter, Irina; Alewood, Paul F; Lewis, Richard J

Comparative Venomics Reveals the Complex Prey Capture Strategy of the Piscivorous Cone Snail Conus catus Journal Article

In: J Proteome Res, vol. 14, no. 10, pp. 4372–4381, 2015, ISSN: 1535-3907.

Abstract | Links | BibTeX | Tags:

Giacomotto, Jean; Rinkwitz, Silke; Becker, Thomas S

Effective heritable gene knockdown in zebrafish using synthetic microRNAs Journal Article

In: Nat Commun, vol. 6, pp. 7378, 2015, ISSN: 2041-1723.

Abstract | Links | BibTeX | Tags:

Punnamoottil, Beena; Rinkwitz, Silke; Giacomotto, Jean; Svahn, Adam J; Becker, Thomas S

Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes Journal Article

In: Genesis, vol. 53, no. 5, pp. 321–328, 2015, ISSN: 1526-968X.

Abstract | Links | BibTeX | Tags:

2013

Giacomotto, Jean; Brouilly, Nicolas; Walter, Ludivine; Mariol, Marie-Christine; Berger, Joachim; Ségalat, Laurent; Becker, Thomas S; Currie, Peter D; Gieseler, Kathrin

Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy Journal Article

In: Hum Mol Genet, vol. 22, no. 22, pp. 4562–4578, 2013, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags:

2012

Djiotsa, Joachim; Verbruggen, Vincianne; Giacomotto, Jean; Ishibashi, Minaka; Manning, Elisabeth; Rinkwitz, Silke; Manfroid, Isabelle; Voz, Marianne L; Peers, Bernard

Pax4 is not essential for beta-cell differentiation in zebrafish embryos but modulates alpha-cell generation by repressing arx gene expression Journal Article

In: BMC Dev Biol, vol. 12, pp. 37, 2012, ISSN: 1471-213X.

Abstract | Links | BibTeX | Tags:

Giacomotto, Jean; Ségalat, Laurent; Carre-Pierrat, Maïté; Gieseler, Kathrin

Caenorhabditis elegans as a chemical screening tool for the study o f neuromuscular disorders. Manual and semi-automated methods Journal Article

In: Methods, vol. 56, no. 1, pp. 103–113, 2012, ISSN: 1095-9130.

Abstract | Links | BibTeX | Tags:

2010

Giacomotto, Jean; Ségalat, Laurent

High-throughput screening and small animal models, where are we? Journal Article

In: Br J Pharmacol, vol. 160, no. 2, pp. 204–216, 2010, ISSN: 1476-5381.

Abstract | Links | BibTeX | Tags:

2009

Giacomotto, Jean; Pertl, Cordula; Borrel, Caroline; Walter, Maggie C; Bulst, Stefanie; Johnsen, Bob; Baillie, David L; Lochmüller, Hanns; Thirion, Christian; Ségalat, Laurent

Evaluation of the therapeutic potential of carbonic anhydrase inhibitors in two animal models of dystrophin deficient muscular dystrophy Journal Article

In: Hum Mol Genet, vol. 18, no. 21, pp. 4089–4101, 2009, ISSN: 1460-2083.

Abstract | Links | BibTeX | Tags:

Blaise, Benjamin J; Giacomotto, Jean; Triba, Mohamed N; Toulhoat, Pierre; Piotto, Martial; Emsley, Lyndon; Ségalat, Laurent; Dumas, Marc-Emmanuel; Elena, Bénédicte

Metabolic profiling strategy of Caenorhabditis elegans by whole-organism nuclear magnetic resonance Journal Article

In: J Proteome Res, vol. 8, no. 5, pp. 2542–2550, 2009, ISSN: 1535-3893.

Abstract | Links | BibTeX | Tags:

2007

Blaise, Benjamin J; Giacomotto, Jean; Elena, Bénédicte; Dumas, Marc-Emmanuel; Toulhoat, Pierre; Ségalat, Laurent; Emsley, Lyndon

Metabotyping of Caenorhabditis elegans reveals latent phenotypes Journal Article

In: Proc Natl Acad Sci U S A, vol. 104, no. 50, pp. 19808–19812, 2007, ISSN: 1091-6490.

Abstract | Links | BibTeX | Tags:

2006

Carre-Pierrat, Maité; Mariol, Marie-Christine; Chambonnier, Lucie; Laugraud, Aurélie; Heskia, Fabienne; Giacomotto, Jean; Ségalat, Laurent

Blocking of striated muscle degeneration by serotonin in C. elegans Journal Article

In: J Muscle Res Cell Motil, vol. 27, no. 3-4, pp. 253–258, 2006, ISSN: 0142-4319.

Abstract | Links | BibTeX | Tags: